Cancer is the second leading cause of death in the United States with over 550,000 deaths in 2009 and a devastating 7.9 million deaths worldwide in 2007. Vascular disrupting agents (VDAs) represent a novel method developed ...
Functionalized benzosuberene analogues represent an emerging class of anticancer agents that are inspired, in part, by combretastatin A-4 (CA4), a natural product found in bark extracts from Combretum caffrum, an African ...