Evaluation of Phenolic Protecting Groups Using Microwave Synthesis and Progress Towards a Benzosuberene Anti-Cancer Agent

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dc.contributor.advisor Pinney, Kevin Khan, Mahmood
dc.contributor.other Baylor University. en_US 2012
dc.description.abstract According to an epidemiology survey conducted by the American Cancer Society, about 1,596,670 new cancer cases were expected to be diagnosed in the year 2011. Cancer is a term used to categorize diseases in which abnormal cells divide uncontrollably and are able to invade normal tissue in the body. Most cancers can be classified into broad categories such as carcinoma, sarcoma, leukemia, lymphoma, and central nervous system cancers. Synthetic chemistry plays a key role in terms of the discovery of new anti-cancer agents. Robust protecting group strategies are paramount in successful target-directed synthetic campaigns. This study investigates the use of a microwave technique compared to conventional heating in the installation of selected phenolic protecting groups. In addition, this thesis covers the progress made towards the synthesis of a new functionalized benzosuberene anti-cancer agent. en_US
dc.rights Baylor University projects are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. Contact for inquiries about permission. en_US
dc.subject Cancer. en_US
dc.subject Benzosuberene. en_US
dc.subject Protecting groups. en_US
dc.subject Vascular Disrupting Agent. en_US
dc.subject Vascular Targeting Agent. en_US
dc.subject Microwave. en_US
dc.subject Conventional. en_US
dc.title Evaluation of Phenolic Protecting Groups Using Microwave Synthesis and Progress Towards a Benzosuberene Anti-Cancer Agent en_US
dc.type Thesis en_US
dc.rights.accessrights Worldwide access. en_US
dc.rights.accessrights Access changed 12/16/14.
dc.contributor.department Chemistry and Biochemistry en_US
dc.contributor.schools honors college en_US

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